Outcomes of 556 consecutive patients with stage I-III colon cancer managed in a single center over 10 years

Το τεκμήριο παρέχεται από τον φορέα :
Ελληνική Γαστροεντερολογική Εταιρία   

Αποθετήριο :
Annals of Gastroenterology   

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στον ιστότοπο του αποθετηρίου του φορέα για περισσότερες πληροφορίες και για να δείτε όλα τα ψηφιακά αρχεία του τεκμηρίου*



Outcomes of 556 consecutive patients with stage I-III colon cancer managed in a single center over 10 years (EN)

Papamichael, Demetris
Vassiliou, Vassilis
Polyviou, Petros
Konstantinou, Ifigenia
Kountourakis, Panteleimon
Xenophontos, Eleni
Vogazianos, Paris

info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

2021-05-05


Background The Bank of Cyprus Oncology Center is the largest cancer center in Cyprus, providing standalone oncology services to a population of just under a million. Methods The aim of the study was to calculate disease-free survival (DFS) and overall survival (OS) for consecutive patients with stage I-III colon cancer over a 10-year period, by collecting retrospective data from patients’ medical charts. Results We identified 556 patients with a median age at diagnosis of 67 (range 18-88). The majority of them were male (60%). Just over half of stage II patients received chemotherapy: capecitabine (44%) and FOLFOX/CapeOx (7%). Treatment administered in stage III was as follows: CapeOx (48%); FOLFOX (28%); capecitabine (12%); 5-fluorouracil (4%); and 8% received no treatment. DFS at 5 years was: stage I 90%; stage II 85%; and stage III 69%. Cancer-specific OS at 5 years was: stage I 94%; stage II 93%; and stage III 81%. Favorable outcomes were also maintained at 10 years (stage I 94%; stage II 84%; and stage III 70%). On multivariate analysis, only stage was statistically significant as a prognostic factor, whereas high-risk features (pT4±pN2), disease location (right vs. left), and age >70 years old did not reach statistical significance. Conclusions Despite our country’s fragmented healthcare system, with multiple referring surgeons from the private and public sectors, the outcomes achieved were highly consistent with those published in the international literature. This can be attributed to optimal multidisciplinary management and follow-up care. Keywords Colon cancer, early stage, single center Ann Gastroenterol 2021; 34 (3): 399-403 (EN)


Αγγλική γλώσσα

Hellenic Society of Gastroenterology (EN)


1792-7463
1108-7471
Annals of Gastroenterology; Volume 34, No 3 (2021); 399 (EN)

Copyright (c) 2021 Annals of Gastroenterology (EN)




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