Outcomes of SARS-CoV-2 infection in patients with celiac disease: a multicenter research network study

Το τεκμήριο παρέχεται από τον φορέα :
Ελληνική Γαστροεντερολογική Εταιρία   

Αποθετήριο :
Annals of Gastroenterology   

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Outcomes of SARS-CoV-2 infection in patients with celiac disease: a multicenter research network study (EN)

Sohail, Amir Humza
Hadi, Yousaf Bashir
Pervez, Asad
Kupec, Justin T.
Naqvi, Syeda Fatima
Lakhani, Dhairya A.

info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

2022-03-21


Background Celiac disease (CD) is associated with an increased risk for respiratory infections and severe outcomes. No data have been reported in the scientific literature regarding the outcomes of COVID-19 in this population. The aim of this study was to report matched clinical outcomes in a large cohort of 930 patients with COVID-19 in the setting of known CD. Methods Analysis of a multicenter research network TriNETX was performed, including COVID-19 patients aged more than 16 years. Outcomes of COVID-19-positive patients with concurrent CD were compared with a propensity-matched cohort of patients without CD. Results A total of 341,499 patients with SARS-CoV-2 infection were identified on the research network: 930 (0.27%) with CD and 340,569 (99.73%) without CD. In the 30- and 60-day periods post SARS-CoV-2 infection, 12 (1.29%) and 13 (1.40%) deaths, respectively, were reported in the CD group. Fewer patients in the CD group reached the composite outcome of either mechanical ventilation or mortality at 60 days (risk ratio 0.58, 95% confidence interval 0.36-0.95). After propensity matching, no difference in clinical outcomes was observed. Conclusion Our data suggest that patients with CD are not at increased risk of COVID-19-related morbidity or mortality. Keywords SARS-CoV-2, COVID-19, celiac disease, morbidity, mortality Ann Gastroenterol 2022; 35 (2): 164-168 (EN)


Αγγλική γλώσσα

Hellenic Society of Gastroenterology (EN)


1792-7463
1108-7471
Annals of Gastroenterology; Volume 35, No 2 (2022); 164 (EN)

Copyright (c) 2022 Annals of Gastroenterology (EN)




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