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Approach to esophageal absent contractility: can we do better?

Το τεκμήριο παρέχεται από τον φορέα :
Ελληνική Γαστροεντερολογική Εταιρία   

Αποθετήριο :
Annals of Gastroenterology   

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Approach to esophageal absent contractility: can we do better? (EN)
Khoury, Tawfik
Abboud, Wisam
Mari, Amir
Cohen, Daniel L
Cohen, Sari
Savarino, Edoardo Vincenzo
Abu Baker, Fadi
Pesce, Marcella
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
2024-03-14
Absent contractility (AC), a motility disorder characterized by the absence of esophageal contractions while maintaining normal lower esophageal sphincter relaxation, is recognized as a distinctive major disorder of peristalsis on esophageal high-resolution manometry that warrants comprehensive understanding. This unique motility disorder often co-occurs with connective tissue, rheumatologic or autoimmune diseases, with scleroderma being the classic example. Symptoms of gastroesophageal reflux are common. AC can profoundly impact patients’ lives and result in a spectrum of complications, including erosive esophagitis, esophageal candidiasis, Barrett’s esophagus, and malnutrition. To address the intricate complexities of AC and its multifaceted complications, a multidisciplinary approach is paramount. This approach considers the distinct clinical presentation and underlying rheumatologic conditions of the individual patient, recognizing the inherent diversity within this disorder. While medical management of gastroesophageal reflux remains the cornerstone of AC treatment, emerging surgical and endoscopic interventions offer additional therapeutic options for those grappling with this challenging condition. This comprehensive review provides an in-depth evaluation of recentadvances in our understanding of AC and its management. It endeavors to offer valuable insights into therapeutic strategies for AC and its associated issues. Keywords Absent contractility, esophageal motility disorders, gastroesophageal reflux disease, diagnosis, management Ann Gastroenterol 2024; 37 (2): 117-124 (EN)
Αγγλική γλώσσα
Hellenic Society of Gastroenterology (EN)
1792-7463
1108-7471
Annals of Gastroenterology; Volume 37, No 2 (2024); 117 (EN)
Copyright (c) 2024 Annals of Gastroenterology (EN)
Ελληνική Γαστροεντερολογική Εταιρία
Annals of Gastroenterology
Invited Review



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