Synchronous gastric gastrointestinal stromal tumor (GIST) and other primary neoplasms of gastrointestinal tract: report of two cases (EN)

Kaur, Ramneet

Jain, Sunila

Nundy, Samiran

Bhalla, Sunita

Gastrointestinal stromal tumors (GIST) are the most common mesenchymal neoplasms of the gastrointestinal tract with a malignant potential. However, uncommonly they can be associated with synchronous tumors of different histogenesis. We herein report two cases of gastric GIST with synchronous tumors. The first case is of a 50-year-old male patient who was suspected with GIST of stomach and was incidentally found to have an associated duodenal neuroendocrine neoplasm. The second case is of a 62-year-old male who, while undergoing surgery for a primary colon adenocarcinoma, was incidentally detected to have a coexistent gastric GIST initially suspected to be a metastatic nodule. Coexistence of gastric GIST with neuroendocrine tumor is extremely rare. To the best of our knowledge this is the second case of gastric GIST coexisting with duodenal neuroendocrine tumor to be reported in the literature. Similarly, association of GIST with adenocarcinoma is uncommon. We herein analyze the pathological findings of two such cases, and we review the malignant potential of these synchronous tumors.Keywords Gastrointestinal stromal tumor, adenocarcinoma, neuroendocrine tumor, synchronous tumors, gastric (EN)

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Ελληνική Γαστροεντερολογική Εταιρία

Annals of Gastroenterology

Case Reports

Αγγλική γλώσσα

2013-09-24

http://www.annalsgastro.gr/index.php/annalsgastro/article/view/1371

Hellenic Society of Gastroenterology (EN)

1792-7463

1108-7471

Annals of Gastroenterology; Volume 26, No 4 (2013); 356 (EN)