Igravemagnetic Resonance Cholangiography in the evaluation of early stage primary sclerosing cholangitis

 
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Annals of Gastroenterology
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Igravemagnetic Resonance Cholangiography in the evaluation of early stage primary sclerosing cholangitis (EN)

S. Chondromatidou, P. Papapostolou, C. Papastergiou,
F. Goutsaridou, K. Tsitouridis, M. Emmanouilidou,, I. Tsitouridis, G. Kouklakis,

SUMMARY Background:The purpose of our study was to evaluate the MR Cholangiographic findings of early stage primary sclerosing cholangitis (PSC). Method:The patients were examined with half fourier – single – shot turbo spin – echo (HASTE), breath hold MR Cholangiography (MRC) using a 1T Siemens Expert Plus Scanner. Axial T2 – Weighted images were also obtained from all patients. We examined 32 patients with a cholestatic biochemical profile positive for primary sclerosing cholangitis. The patients were divided into two groups according the degree of the abnormality of the values of the biochemical data. A third group of 20 men and 5 women with normal biochemical profile also were examined. Results: The first group comprised 11 patients with mild disturbance of biochemical profile showing a mild increase in signal intensity on T2WI in liver parenchyma and haziness of the margins of the intrahepatic bile ducts, due to inflammation, at MRC cholangiography. The second group comprised 21 patients with more stable increase of the biochemical profile. MRC findings were haziness of the bile duct margins due to inflammation and areas with dilatation of bile duct branches due to stenosis from fibrosis. From the third group, we found a mild increase in signal intensity on T2WI in the liver parenchyma and haziness of the margins of the intirhepatic bile duct in 2 men with normal laboratory data. Conclusion: This study suggests that MRC can be used for the detection of early stage primary sclerosing cholangitis, but it has low specificity in the characterization of this disease. Although the method has low specificity, it is the method of choice to evaluate this disease, if findings are combined with positive laboratory data. Key words: Bile ducts diseases, MR Cholangiography, Cholangitis (EN)

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info:eu-repo/semantics/publishedVersion

Ελληνική Γαστροεντερολογική Εταιρία (EL)
Hellenic Society of Gastroenterology (EN)

2007-03-19


Hellenic Society of Gastroenterology (EN)

1792-7463
1108-7471
Annals of Gastroenterology; Volume 17, No 3 (2004) (EN)



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