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BUBBLES, CLUSTERS AND DENATURATION IN GENOMIC DNA: MODELING, PARAMETRIZATION, EFFICIENT COMPUTATION

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BUBBLES, CLUSTERS AND DENATURATION IN GENOMIC DNA: MODELING, PARAMETRIZATION, EFFICIENT COMPUTATION
Θεοδωρακόπουλος, Νίκος
Άρθρο σε επιστημονικό περιοδικό
2011-08
The paper uses mesoscopic, nonlinear lattice dynamics based (Peyrard-Bishop-Dauxois, PBD) modeling to describe thermal properties of DNA below and near the denaturation temperature. Computationally efficient notation is introduced for the relevant statistical mechanics. Computed melting profiles of long and short heterogeneous sequences are presented, using a recently introduced reparametrization of the PBD model, and critically discussed. The statistics of extended open bubbles and bound clusters is formulated and results are presented for selected examples.
Singapore
Φυσική (EL)
Physics (EN)
Peyrard-Bishop-Dauxois (PBD) model
DNA melting
Physics, Mathematical
denaturation bubbles
English
World Scientific Publ Company Pte Limited
Journal of Nonlinear Mathematical Physics
© WORLD SCIENTIFIC PUBL CO PTE LTD
© WORLD SCIENTIFIC PUBL CO PTE LTD (EN)
National Hellenic Research Foundation (NHRF)
Helios - Repository of the National Hellenic Research Foundation (NHRF)



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