Controlled release of newer quinolones from biodegradable systems based on poly(lactic acid)

 
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1995 (EN)
Controlled release of newer quinolones from biodegradable systems based on poly(lactic acid) (EN)

Andreopoulos, AG (EN)

N/A (EN)

The release of newer quinolones (such as pefloxacin, ofloxacin, and ciprofloxacin) from biodegradable poly(D,L lactic acid) has been investigated. The in vitro study showed that drug delivery takes place for about two months and a maximum in concentration was recorded after fifteen days. The release from poly(lactic acid) slabs seemed to give high drug doses that are adequate for the treatment of infections caused by common pathogens. (EN)

journalArticle

lactic acid (EN)
polymer (EN)
biodegradable (EN)
resomer (EN)
Escherichia coli (EN)
pefloxacin (EN)
in vitro study (EN)
antiinfective agent (EN)
Anti-Infective Agents (EN)
Quinolones (EN)
Drug Delivery Systems (EN)
ofloxacin (EN)
Microorganisms (EN)
Controlled drug delivery (EN)
polylactic acid (EN)
Time Factors (EN)
Aromatic compounds (EN)
Polymers (EN)
Biodegradation (EN)
chemistry (EN)
delayed release formulation (EN)
Lactic Acid (EN)
Polylactic acid (EN)
Membranes, Artificial (EN)
4-Quinolones (EN)
Organic polymers (EN)
Resomer (EN)
Biodegradable systems (EN)
Ofloxacin (EN)
article (EN)
Infection (EN)
lactic acid derivative (EN)
Drug products (EN)
Lactates (EN)
controlled release (EN)
Pefloxacin (EN)
4 quinolone derivative (EN)
quinolones (EN)
artificial membrane (EN)
drug delivery system (EN)
time (EN)
Ciprofloxacin (EN)
Delayed-Action Preparations (EN)
ciprofloxacin (EN)

Εθνικό Μετσόβιο Πολυτεχνείο (EL)
National Technical University of Athens (EN)

Journal of Biomaterials Applications (EN)

1995


Technomic Publ Co Inc, Lancaster, PA, United States (EN)



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