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Laser induced autofluorescence studies of animal skin used in modeling of human cutaneous tissue spectroscopic measurements

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National Technical University of Athens   

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Laser induced autofluorescence studies of animal skin used in modeling of human cutaneous tissue spectroscopic measurements (EN)
Borisova, E (EN)
Angelov, I (EN)
Drakaki, E (EN)
Serafetinides, AA (EN)
Makropoulou, M (EN)
Avramov, L (EN)
journalArticle (EN)
2014-03-01T01:26:33Z
2007 (EN)
Background/purpose: Laser-induced autofluorescence spectroscopy provides excellent possibilities for medical diagnostics of different tissue pathologies including cancer. However, to create the whole picture of pathological changes, investigators collect spectral information from patients in vivo or they study different tumor models to obtain objective information for fluorescent properties of every kind of healthy and diseased tissue. Therefore, it is very important to find the most appropriate, and close to the human skin, animal samples from the fluorescence point of view, which will allow the extrapolation of the animal data to human spectroscopic diagnostics. Methods: In the present work, we examined the autofluorescence properties of different animal skin tissues, which are considered as the most common skin models. A nitrogen laser was used as an excitation source. Samples of healthy mouse, chicken and pig skin in vivo and/or ex vivo were studied and were compared with results obtained from investigations of healthy human skin in vivo. Results and conclusion: Specific features of the recorded spectra are discussed and the possible origin of the obtained fluorescence signals is proposed. Quantitative evaluation of data extrapolation for each skin type is also depicted. © 2007 Blackwell Munksgaard. (EN)
Dermatology (EN)
Animal model (EN)
chicken (EN)
Post mortem (EN)
Species Specificity (EN)
Humans (EN)
Fluorescence (EN)
skin (EN)
Human skin (EN)
autofluorescence (EN)
Tissue (EN)
excitation (EN)
skin examination (EN)
spectroscopy (EN)
Lasers (EN)
Swine (EN)
Laser spectroscopy (EN)
Models, Animal (EN)
Diagnosis (EN)
quantitative analysis (EN)
Spectrum Analysis (EN)
human (EN)
ex vivo study (EN)
Laser induced fluorescence spectroscopy (EN)
human tissue (EN)
Laser-induced autofluorescence spectroscopy (EN)
Dermatology (EN)
nitrogen (EN)
Skin Physiology (EN)
sampling (EN)
Cutaneous tissue (EN)
in vivo study (EN)
article (EN)
swine (EN)
In vivo (EN)
Pathology (EN)
Animals (EN)
controlled study (EN)
Chickens (EN)
animal tissue (EN)
Skin (EN)
nonhuman (EN)
Mice (EN)
disease model (EN)
Skin Research and Technology (EN)
English
BLACKWELL PUBLISHING (EN)
National Technical University of Athens
Digital Library of National Technical University of Athens | Dspace@NTUA
Κεντρική Βιβλιοθήκη Ε.Μ.Π.
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