Spiradenocylindrocarcinoma. Report of a case with a low-grade component of spiradenocarcinoma and an immunohistochemical study

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Spiradenocylindrocarcinoma. Report of a case with a low-grade component of spiradenocarcinoma and an immunohistochemical study (EN)

Apostolou, G (EN)
Chatzipantelis, P (EN)
Biteli, M (EN)
Apostolou, N (EN)

journalArticle (EN)

2014-03-01T01:31:58Z
2009 (EN)


Spiradenocylindrocarcinoma is a very rare malignant cutaneous neoplasm of the folliculosebaceous-apocrine unit. We report a case of this hybrid tumor in a 42-year-old woman. The tumor consisted of 2 circumscribed nodules with areas of cylindrocarcinoma and low-grade spiradenocarcinoma. In the overlapping areas, both spiradenomatous and cylindromatous features were observed. Expansion of the tumor beyond the fibrous pseudocapsule into the adjacent tissue was present. Furthermore, tumor cells were demonstrating mild to moderate pleomorphism and an increased mitotic index. p53 and ki-67 were among the positive immunohistochemical markers. A relatively small number of tumor cells expressed estrogen receptors. The aim of this study was to investigate the nature of this rare tumor of the skin appendages. © 2009 Lippincott Williams & Wilkins, Inc. (EN)

Dermatology (EN)

Immunohistochemistry (EN)
Ki 67 antigen (EN)
cancer surgery (EN)
Humans (EN)
mixed tumor (EN)
cycline (EN)
cancer cell (EN)
cytokeratin 5 (EN)
cytokeratin 8 (EN)
epithelial membrane antigen (EN)
cytokeratin 7 (EN)
spiradenocylindroma (EN)
female (EN)
hidradenoma (EN)
cancer diagnosis (EN)
mitosis (EN)
article (EN)
subcutaneous tissue (EN)
scar (EN)
skin appendage (EN)
cancer recurrence (EN)
Skin Neoplasms (EN)
adult (EN)
Carcinoma, Skin Appendage (EN)
genetic polymorphism (EN)
Estrogen receptor (EN)
Spiradenocylindroma (EN)
case report (EN)
progesterone receptor (EN)
cancer grading (EN)
Spiradenocylindrocarcinoma (EN)
Adult (EN)
Female (EN)
immunohistochemistry (EN)
priority journal (EN)
human (EN)
cylindroma (EN)
carcinoembryonic antigen (EN)
cytokeratin 20 (EN)
Tumor Markers, Biological (EN)
human tissue (EN)
estrogen receptor (EN)
protein p53 (EN)
Neoplasm Recurrence, Local (EN)
Apocrine (EN)
Adnexal neoplasm (EN)
cytokeratin 18 (EN)
cytokeratin 19 (EN)
cytokeratin 14 (EN)
cytokeratin 17 (EN)
cytokeratin 10 (EN)
cytokeratin 13 (EN)

American Journal of Dermatopathology (EN)

English

LIPPINCOTT WILLIAMS & WILKINS (EN)




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