Downgrading BIRADS 3 to BIRADS 2 category using a computer-aided microcalcification analysis and risk assessment system for early breast cancer

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Downgrading BIRADS 3 to BIRADS 2 category using a computer-aided microcalcification analysis and risk assessment system for early breast cancer (EN)

Spyrou, GM (EN)
Antaraki, A (EN)
Andreadis, I (EN)
Giannakopoulou, G (EN)
Nonni, A (EN)
Ligomenides, PA (EN)
Filippakis, GM (EN)
Nikita, KS (EN)
Zografos, GC (EN)
Koulocheri, D (EN)
Zagouri, F (EN)

journalArticle (EN)

2014-03-01T01:33:10Z
2010 (EN)


This paper explores the potential of a computer-aided diagnosis system to discriminate the real benign microcalcifications among a specific subset of 109 patients with BIRADS 3 mammograms who had undergone biopsy, thus making it possible to downgrade them to BIRADS 2 category. The system detected and quantified critical features of microcalcifications and classified them on a risk percentage scale for malignancy. The system successfully detected all cancers. Nevertheless, it suggested biopsy for 11/15 atypical lesions. Finally, the system characterized as definitely benign (BIRADS 2) 29/88 benign lesions, previously assigned to BIRADS 3. and thus achieved a reduction of 33% in unnecessary biopsies. (C) 2010 Elsevier Ltd. All rights reserved. (EN)

Computer Science, Interdisciplinary Applications (EN)
Engineering, Biomedical (EN)
Biology (EN)
Mathematical & Computational Biology (EN)

risk assessment (EN)
Microcalcifications (EN)
Diagnosis, Computer-Assisted (EN)
major clinical study (EN)
Humans (EN)
Middle Aged (EN)
SVABB (EN)
BI-RADS (EN)
Breast Neoplasms (EN)
BIRADS 3 (EN)
cancer grading (EN)
Risk assessment (EN)
breast biopsy (EN)
Aged, 80 and over (EN)
Medical computing (EN)
Adult (EN)
Female (EN)
computer aided microcalcification analysis (EN)
Computer aided diagnosis (EN)
priority journal (EN)
female (EN)
computer aided design (EN)
early cancer (EN)
human (EN)
Computer aided analysis (EN)
human tissue (EN)
mammography (EN)
Risk Assessment (EN)
CAD system (EN)
aged (EN)
breast cancer (EN)
cancer diagnosis (EN)
Mammography (EN)
Risk analysis (EN)
article (EN)
Biopsy (EN)
Calcinosis (EN)
Aged (EN)
Early breast cancer (EN)
adult (EN)

Computers in Biology and Medicine (EN)

English

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