Familial cases of poikiloderma of Civatte: genetic implications in its pathogenesis?

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Title

Familial cases of poikiloderma of Civatte: genetic implications in its pathogenesis? (EN)

Creator

Georgala, S (EN)

Katsarou-Katsari, A (EN)

Koumantaki-Mathioudaki, E (EN)

Antoniou, C (EN)

Stratigos, JD (EN)

Katoulis, AC (EN)

Stavrianeas, NG (EN)

Type

journalArticle (EN)

Partial document
Publication in journal (EN)

Article
Scientific article (EN)

Issued

2014-03-01T01:48:53Z

1999 (EN)

Year

1999 (EN)

Description

Poikiloderma of Civatte (PC) is a rather common, benign skin condition of obscure etiopathogenesis: cumulative exposure to UV radiation, hormonal changes associated with the menopause, and photo-allergic mechanisms have been implicated. We present seven cases of PC among the members of two unrelated Greek families, who have not shared common extrinsic influences, Literature review revealed no other reported familial cases. Familial tendencies, as well as the not unusual occurrence of PC in individuals with minimal sun exposure, and who are not using perfumes or cosmetics, provide support for the hypothesis that a genetic predisposition to the disease may exist; this predisposition is possibly transmitted as an autosomal dominant trait. (EN)

Scientific field

Dermatology (EN)

Medical and Health Sciences ▶ Clinical Medicine
Dermatology (EN)

Journal

CLINICAL AND EXPERIMENTAL DERMATOLOGY (EN)

Language

English

Publisher

BLACKWELL SCIENCE LTD (EN)

Provider

National Technical University of Athens

Repository / collection