Thyroid function in patients with Alzheimer's disease treated with cholinesterase inhibitors

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Title

Thyroid function in patients with Alzheimer's disease treated with cholinesterase inhibitors (EN)

Creator

Ilias, I (EN)

Theotoka, I (EN)

Paraskevas, GP (EN)

Christakopoulou, I (EN)

Kapaki, E (EN)

Type

journalArticle (EN)

Partial document
Publication in journal (EN)

Article
Scientific article (EN)

Issued

2014-03-01T01:53:14Z

2003 (EN)

Year

2003 (EN)

Description

The aim of the present study was to explore a possible interplay between cholinesterase inhibitors (ChEIs) and thyroid function tests (TFTs) in patients with Alzheimer's disease (AD). We reviewed thyroid function tests in 19 patients with AD before and after treatment (Rx) with ChEIs. Immunoradiometric assays were used for measuring serum thyrotropin, free thyroxin (FT4) and free triiodothyronine (FT3). Significant differences were observed among FT3 levels according to the duration of therapy. Subtle variations in thyroid function tests - before and after therapy - could be possibly related to ChEIs-induced altered thyroid function. (EN)

Scientific field

Neurosciences (EN)

Medical and Health Sciences ▶ Basic Medicine
Neurosciences (EN)

Subject

DEMENTIA (EN)

ACETYLCHOLINE (EN)

thyroid function tests (EN)

cholinesterase inhibitors (EN)

TRH STIMULATION TEST (EN)

COGNITION (EN)

Alzheimer's disease (EN)

BRAIN (EN)