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The effect of prostaglandin analogues ( latanoprost, travoprost and bimatoprost) on central corneal thickness of patients with chronic open angle glaucoma

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Επίδραση της χρήσεως των αναλόγων των προσταγλανδινών ( λατανοπρόστης, τραβοπρόστης και μπιματοπρόστης) στο κεντρικό πάχος του κερατοειδούς ασθενών με χρόνιο γλαύκωμα
The effect of prostaglandin analogues ( latanoprost, travoprost and bimatoprost) on central corneal thickness of patients with chronic open angle glaucoma
Bafa, Maria
Μπάφα, Μαρία
PhD Thesis
2009
Purpose: To evaluate the effect of prostaglandin analogues on the central corneal thickness (CCT) of patients with chronic open-angle glaucoma (COAG). Methods: 129 eyes participated in this study. Of these, 108 eyes were treated with prostaglandin analogues (latanoprost, travoprost and bimatoprost), while 21 eyes treated with b-blockers were used as controls. CCT was measured before treatment and at three-month intervals. Results: A slight but significant increase in CCT was recorded in the bimatoprost and latanoprost groups. Treatment with bimatoprost produced a constant increase (1, 85- 8, 83 μm) in CCT at all time points of the study. The CCT rise found in the latanoprost group was significant for the first year. Treatment with travoprost did not affect CCT. Conclusions: The possibility of corneal thickening under prolonged, local prostaglandin treatment should be investigated further. However, in clinical practice, CCT changes may sometimes influence intraocular pressure measurements significantly.
Ιατρική και Επιστήμες Υγείας ➨ Κλινική Ιατρική
Glaucoma
Ultrasound pachymetry
Ενδοφθάλμια πίεση
Medical and Health Sciences
Υπερηχογραφική παχυμετρία
Κλινική Ιατρική
Clinical Medicine
Prostaglandins
Central corneal thickness
Κερατοειδής, Κεντρικό πάχος
Γλαύκωμα
Ιατρική και Επιστήμες Υγείας
Προσταγλανδίνες
Intraocular pressure
Greek
National and Kapodistrian University of Athens
Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ)
Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών (ΕΚΠΑ). Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής. Κλινική Β' Πανεπιστημιακή Οφθαλμολογική Αθηνών
National Documentation Centre (EKT)
National Archive of PhD Theses
Συλλογή ΕΑΔΔ



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