δείτε την πρωτότυπη σελίδα τεκμηρίου
στον ιστότοπο του αποθετηρίου του φορέα για περισσότερες πληροφορίες και για να δείτε όλα τα ψηφιακά αρχεία του τεκμηρίου*



Synthesis and properties of poly(lactic acid) (EN)

Doxastakis, M (EN)
Hatzi, E (EN)
Andreopoulos, AG (EN)

journalArticle (EN)

2014-03-01T01:15:16Z
1999 (EN)


Poly(D,L lactic acid) was prepared by bulk polymerization of D,L lactide, both under atmospheric pressure and in vacuum. The obtained polymeric products were characterized in terms of molecular weight, M(w), melting point, calorimetric response and swelling behaviour. All products were amorphous. Their molecular weights were determined by viscosimetry and ranged from 2 x 103 to 9 x 104. Similarly, the melting points ranged from 90 to 210°C. Swelling experiments, with specimens immersed in buffer solutions, showed that hydrolytic degradation started in a few days for the low M(w) material, whereas for the higher molecular weight products it took much longer and probably followed a two-stage mechanism. This study suggests that the high molecular weight material could be an interesting carrier for the preparation of controlled release products, in cases where prolonged delivery is necessary.Poly(D,L lactic acid) was prepared by bulk polymerization of D,L lactide, both under atmospheric pressure and in vacuum. The obtained polymeric products were characterized in terms of molecular weight, Mw, melting point, calorimetric response and swelling behaviour. All products were amorphous. Their molecular weights were determined by viscosimetry and ranged from 2×103 to 9×104. Similarly, the melting points ranged from 90 to 210 °C. Swelling experiments, with specimens immersed in buffer solutions, showed that hydrolytic degradation started in a few days for the low Mw material, whereas for the higher molecular weight products it took much longer and probably followed a two-stage mechanism. This study suggests that the high molecular weight material could be an interesting carrier for the preparation of controlled release products, in cases where prolonged delivery is necessary. (EN)

Engineering, Biomedical (EN)
Materials Science, Biomaterials (EN)

lactic acid (EN)
polymerization (EN)
Molecular Weight (EN)
Atmospheric pressure (EN)
Biosynthesis (EN)
Atmospheric Pressure (EN)
Molecular weight (EN)
Biomaterials (EN)
polylactic acid (EN)
vacuum (EN)
High Molecular Weight (EN)
Polyesters (EN)
Viscosity measurement (EN)
priority journal (EN)
Vacuum applications (EN)
Biodegradation (EN)
melting point (EN)
viscometry (EN)
Swelling (EN)
Lactic Acid (EN)
Polylactic acid (EN)
Polymerization (EN)
molecular weight (EN)
article (EN)
Hydrolysis (EN)
Controlled Release (EN)
Calorimetry (EN)
Melting point (EN)
hydrolysis (EN)

Journal of Materials Science: Materials in Medicine (EN)

Αγγλική γλώσσα

Kluwer Academic Publishers, Dordrecht, Netherlands (EN)




*Η εύρυθμη και αδιάλειπτη λειτουργία των διαδικτυακών διευθύνσεων των συλλογών (ψηφιακό αρχείο, καρτέλα τεκμηρίου στο αποθετήριο) είναι αποκλειστική ευθύνη των αντίστοιχων Φορέων περιεχομένου.