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Prognostic factors for the response to treatment in males with genital warts

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Prognostic factors for the response to treatment in males with genital warts (EN)
Katzouranis, I (EN)
Caroni, C (EN)
Bethimoutis, G (EN)
Katsambas, A (EN)
Nicolaidou, E (EN)
Hadjivassiliou, M (EN)
Anyfantakis, V (EN)
Antoniou, C (EN)
Panagiotopoulos, A (EN)
Stefanaki, C (EN)
Lagogianni, E (EN)
journalArticle (EN)
2014-03-01T01:31:42Z
2009 (EN)
Background Factors predicting an unfavourable course of genital warts to treatment have not been determined. Materials and methods Behavioural and baseline disease characteristics were recorded from 246 males with anogenital warts. Urethral swabs were obtained and examined using the Hybrid Capture 2 Microplate assay. Patients were treated for their anogenital warts with cryotherapy, imiquimod cream 5% or podophyllotoxin. They were followed up every 3 months for 1 year. Results Patients with a negative or low-risk initial test tended to respond earlier to treatment than those with a high/intermediate-risk human papillomavirus (HPV) or with a dual infection (P = 0.028). The response rate was unrelated (P > 0.05) to the duration, number and anatomical location of the lesions and to the patient's age and sexual orientation, and only marginally to the initial extent of the lesion (P = 0.046). However, the type of treatment predicted a favourable response (P ≤ 0.001), with patients who received both imiquimod and crotherapy responding worse. Considering all factors simultaneously in logistic regression, only the type of treatment and extent of the disease were found to influence the response rate. Conclusion The type of treatment and extent of the disease were the only factors found critical for patients' response. © 2009 European Academy of Dermatology and Venereology. (EN)
Dermatology (EN)
Podophyllinotoxin (EN)
Prognosis (EN)
Podophyllotoxin (EN)
Imiquimod (EN)
major clinical study (EN)
sexual orientation (EN)
Humans (EN)
Middle Aged (EN)
Male (EN)
urethra (EN)
Wart virus (EN)
HPV (EN)
follow up (EN)
Anus Diseases (EN)
Genital warts (EN)
podophyllotoxin (EN)
DNA determination (EN)
mixed infection (EN)
Adult (EN)
Genital Diseases, Male (EN)
priority journal (EN)
diagnostic value (EN)
disease duration (EN)
condyloma acuminatum (EN)
disease severity (EN)
human (EN)
Condylomata Acuminata (EN)
Combined Modality Therapy (EN)
cryotherapy (EN)
virus DNA (EN)
prognosis (EN)
article (EN)
clinical feature (EN)
infection risk (EN)
age distribution (EN)
educational status (EN)
treatment response (EN)
imiquimod (EN)
Adolescent (EN)
adolescent (EN)
adult (EN)
Cryotherapy (EN)
male (EN)
Aminoquinolines (EN)
Journal of the European Academy of Dermatology and Venereology (EN)
English
WILEY-BLACKWELL PUBLISHING, INC (EN)
National Technical University of Athens
Digital Library of National Technical University of Athens | Dspace@NTUA
Κεντρική Βιβλιοθήκη Ε.Μ.Π.
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