Solid-phase synthesis of optically active substituted 2-aminofuranones using an activated carbonate linker

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Solid-phase synthesis of optically active substituted 2-aminofuranones using an activated carbonate linker (EN)

Matiadis, D (EN)
Prousis, KC (EN)
Igglessi-Markopoulou, O (EN)

journalArticle (EN)

2014-03-01T01:31:56Z
2009 (EN)


An efficient three-step solid-phase synthesis of diverse 3,5-disubstituted-2-aminofuranones has been developed. alpha-Hydroxy acids loaded on a nitrophenyl carbonate derivative of Wang resin are used as acylating agents for the C-acylation of active methylene compounds and the resulting intermediates provided, through a cyclative cleavage reaction, the desired product. (EN)

Chemistry, Organic (EN)

chemistry (EN)
synthesis (EN)
Heterocycles (EN)
2-aminofuranones (EN)
carbonic acid derivative (EN)
polystyrene derivative (EN)
Hydroxy Acids (EN)
Solid-phase synthesis (EN)
acylation (EN)
article (EN)
Lactones (EN)
furan derivative (EN)
Acylations (EN)
Polystyrenes (EN)
Furans (EN)
Carbonates (EN)
hydroxyacid (EN)
Wang resin (EN)
Acylation (EN)

Molecules (EN)

English

MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL-MDPI (EN)




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