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Acylaminoacetyl derivatives of active methylene compounds .4. Synthesis of N-protected tetramic acids via the C-acylation reaction of Meldrum's acid with the imidazolides of N-protected glycines

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Acylaminoacetyl derivatives of active methylene compounds .4. Synthesis of N-protected tetramic acids via the C-acylation reaction of Meldrum's acid with the imidazolides of N-protected glycines (EN)
Sandris, C (EN)
Hamilakis, S (EN)
Kontonassios, D (EN)
journalArticle (EN)
2014-03-01T01:44:59Z
1996 (EN)
Meldrum's acid has been found to be effectively acylated using the imidazolides of N-protected glycines, X-NHCH2COOH (X = -COPh, -COMe, -Z, -Boc, -COOMe and -COOEt). The corresponding C-acylation compounds were isolated in high yields and were readily converted to the N-protected tetramic acids. It was shown by pmr spectroscopy that these acids exist as the enol tautomers in DMSO-d(6) solution, whereas in deuteriochloroform solution both the enol and keto tautomers can be observed. (EN)
Chemistry, Organic (EN)
JOURNAL OF HETEROCYCLIC CHEMISTRY (EN)
English
HETERO CORPORATION (EN)
National Technical University of Athens
Digital Library of National Technical University of Athens | Dspace@NTUA
Κεντρική Βιβλιοθήκη Ε.Μ.Π.
Ιδρυματικό Αποθετήριο
Δημοσιεύσεις μελών Δ.Ε.Π. σε περιοδικά



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