Superficial Siderosis of Central Nervous System Mimicking Multiple Sclerosis

δείτε την πρωτότυπη σελίδα τεκμηρίου
στον ιστότοπο του αποθετηρίου του φορέα για περισσότερες πληροφορίες και για να δείτε όλα τα ψηφιακά αρχεία του τεκμηρίου*



Superficial Siderosis of Central Nervous System Mimicking Multiple Sclerosis (EN)

Papadimas, GK (EN)
Evdokimidis, I (EN)
Konstantinopoulou, A (EN)
Kokotis, P (EN)
Zouvelou, V (EN)
Rentzos, M (EN)
Kilidireas, K (EN)

journalArticle (EN)

2014-03-01T01:58:59Z
2009 (EN)


Introduction: Superficial siderosis of the central nervous system is a neurologic disorder mainly characterized by cerebellar involvement, myelopathy, neurosensory hearing loss, and possibly progressive cognitive impairment. Root avulsion due to traumatic plexus injury has been recognized as an extremely rare cause of hemosiderin deposition oil leptomeninges and subpial layers of brain and spinal cord parenchyma. Case Report: A 49-year-old mail presented with progressively evolving ataxia and spastic paraparesis. CSF oligoclonal bands were indicative of an underlying inflammatory process and raised the possibility of a demyelinating disorder. However, spinal cord and brain MRI revealed hemosiderin deposition along the entire neuraxis. A rigorous electrophysiologic study confirmed a functional impairment in many different levels of the nervous system. Conclusion: The demonstration of CSF oligoclonal bands in the reported patient implies that inflammation might be involved in the pathogenesis of superficial siderosis. The diagnosis of this newly recognizable entity needs a high clinical suspicion, but further research is needed to fully elucidate the involved mechanisms. (EN)

Clinical Neurology (EN)

oligoclonal hands (EN)
multiple sclerosis (EN)
superficial siderosis (EN)

NEUROLOGIST (EN)

Αγγλική γλώσσα

LIPPINCOTT WILLIAMS & WILKINS (EN)




*Η εύρυθμη και αδιάλειπτη λειτουργία των διαδικτυακών διευθύνσεων των συλλογών (ψηφιακό αρχείο, καρτέλα τεκμηρίου στο αποθετήριο) είναι αποκλειστική ευθύνη των αντίστοιχων Φορέων περιεχομένου.