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Cyclosporin: A therapy for allergic cutaneous vasculitis with multiple recurrences

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Cyclosporin: A therapy for allergic cutaneous vasculitis with multiple recurrences
Stratigos, J. Katsambas, A. Potouridou, E.
scientific_publication_article
Επιστημονική δημοσίευση - Άρθρο Περιοδικού (EL)
Scientific publication - Journal Article (EN)
1994
Cyclosporin (CyA) was used to treat 13 patients suffering from allergic cutaneous vasculitis (AVC) with multiple recurrences. CyA at a dose of 5 mg/kg was administered orally for the first 2 months. For the following 4 months, CyA at a dose of 2.5 mg/kg alone or in combination with prednisolone was used, depending on the clinical response. Clinical and laboratory examinations were performed once weekly throughout the study period. Seven patients remained in excellent condition under CyA (2.5 mg/kg) monotherapy. Three patients showed an excellent response to the combination of CyA (2.5 mg kg) and prednisolone (10 mg/24 h). Finally, in three patients the treatment was discontinued during the first month because the creatinine level increased by more than 30% of the initial value. This study shows that CyA alone or in combination with prednisolone is an effective treatment for ACV with multiple recurrences. © 1994 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. (EN)
English
Ερευνητικό υλικό ΕΚΠΑ
https://creativecommons.org/licenses/by-nc/4.0/
University of Athens
Pergamos Digital Library
Journal Article



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