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Safety and pharmacokinetics of oseltamivir for prophylaxis of neonates exposed to influenza H1N1

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Safety and pharmacokinetics of oseltamivir for prophylaxis of neonates exposed to influenza H1N1
Maltezou, H.C. Drakoulis, N. Siahanidou, T. Karalis, V. Zervaki, E. Dotsikas, Y. Loukas, Y.L. Theodoridou, M.
scientific_publication_article
Επιστημονική δημοσίευση - Άρθρο Περιοδικού (EL)
Scientific publication - Journal Article (EN)
2012
Oseltamivir was administered at 1.0 mg/kg b.i.d. to 13 neonates exposed to influenza H1N1. No influenza, neurologic, or laboratory adverse effects occurred. The mean Cmax values for oseltamivir and oseltamivir carboxylate were found to be lower than those reported for children 1 to 5 years old, whereas Tmax values were similar to children 1 to 5 years old. Age and gender were found to significantly affect oseltamivir clearance. Copyright © 2012 by Lippincott Williams & Wilkins. (EN)
English
Ερευνητικό υλικό ΕΚΠΑ
https://creativecommons.org/licenses/by-nc/4.0/
University of Athens
Pergamos Digital Library
Journal Article



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