Current development in tissue-engineered vascular grafts

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Current development in tissue-engineered vascular grafts

Tsatsaris, A. Perrea, D.

scientific_publication_article
Επιστημονική δημοσίευση - Άρθρο Περιοδικού (EL)
Scientific publication - Journal Article (EN)

2007


Vascular tissue engineering has been hailed as a breakthrough in reconstructive vessel surgery. The traditional method includes either vessel substitution with an artificial graft or an autologous compatible tissue. For artificial grafts, some limitations are inevitable (e.g. thrombotic complications) and they cannot be used in substitution of small-caliber arterial vessels. On the other hand, the use of autologous donor-vessels is often restricted due to concomitant disease. The main aim of vascular tissue engineering is to provide biological artery substitutes by combining cellular components with biodegradable scaffolds. In this review, current approaches to vascular tissue engineering and the possible involvement of specific gene expression are discussed. © 2007 Bentham Science Publishers Ltd. (EN)

English

Ερευνητικό υλικό ΕΚΠΑ

https://creativecommons.org/licenses/by-nc/4.0/




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