The Impact of Whole Sesame Seeds on the Expression of Key-Genes Involved in the Innate Immunity of Dairy Goats

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The Impact of Whole Sesame Seeds on the Expression of Key-Genes Involved in the Innate Immunity of Dairy Goats

Flemetakis, Emmanouil
Tsiplakou, Eleni
Sotirakoglou, Kyriaki
Skliros, Dimitrios
Mitsiopoulou, Christina

article

2023-07-25T10:24:30Z
2021-02-10


Whole sesame seeds (WSS) are rich in both linoleic acid (LA) and lignans. However, their impact on the innate immunity of goats is not well studied. Twenty-four goats were divided into three homogeneous sub-groups; comprise one control (CON) and two treated (WWS5 and WWS10). In the treated groups, WSS were incorporated in the concentrates of the CON at 5 (WSS5) and 10% (WSS10) respectively, by partial substitution of both soybean meal and corn grain. The expression levels of MAPK1, IL6, TRIF, IFNG, TRAF3, and JUND genes in the neutrophils of WSS10 fed goats were reduced significantly compared with the CON. The same was found for the expression levels of IFNG and TRAF3 genes in the neutrophils of WSS5 fed goats. Both treated groups primarily affected the MYD88-independent pathway. The dietary supplementation of goats with WSS might be a good nutritional strategy to improve their innate immunity.

Engineering and Technology
Environmental Biotechnology

Engineering and Technology
Goats
Neutrophils
Innate immunity
Environmental Biotechnology
Whole sesame seeds
Blood

Αγγλική γλώσσα

Animals, 2021, vol. 11, iss. 2, pp. 1 - 14

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