1. Home page
  2. Search

Low and high body mass index in hidradenitis suppurativa patients—different subtypes?

This item is provided by the institution :
/aggregator-openarchives/portal/institutions/uoa   

Repository :
Pergamos Digital Library   

see the original item page
in the repository's web site and access all digital files if the item*



Low and high body mass index in hidradenitis suppurativa patients—different subtypes?
Theut Riis, P. Saunte, D.M. Benhadou, F. del Marmol, V. Guillem, P. El-Domyati, M. Abdel-Wahab, H. Antoniou, C. Dessinioti, C. Gürer, M.A. Beksaç, B. Szepietowski, J.C. Matusiak, L. Emtestam, L. Lapins, J. Riad, H. Doss, N. Massa, A.F. Hamzavi, I. Nicholson, C. Dolenc-Voljc, M. Kim, K.H. Ohn, J. Zouboulis, C.C. Karagiannidis, I. Mokos, Z.B. Durinec, P. Jemec, G.B.E.
scientific_publication_article
Επιστημονική δημοσίευση - Άρθρο Περιοδικού (EL)
Scientific publication - Journal Article (EN)
2018
Introduction: Overweight is a well-established risk factor for hidradenitis suppurativa (HS). In this cross-sectional study, we compare HS patients with a high body mass index (BMI) with HS patients with a low BMI to investigate differences in disease characteristics. Materials and method: Patients were recruited from 17 dermatological centres from four continents. A total of 246 patients with a BMI below 25 were compared to 205 patients with a BMI of above 35. Results: Patients with a high BMI suffered more severe disease (Hurley, physician global assessment, number of areas affected and patient-reported severity (PRS), P < 0.001 for all). There was no difference in smoking (P = 0.783) nor in family history (P = 0.088). In both low and high BMI patients, early onset of HS was a predictor of positive family history (P < 0.001, for each). For low BMI patients, an increase in BMI significantly increased PRS (P < 0.001). For patients with a high BMI, number of pack-years significantly increased PRS (P = 0.001). Cluster analysis of eruption patterns was location specific for low BMI patients but severity specific for high BMI patients. Discussion: Patients with a low and high BMI could represent two clinically different subtypes. We suggest a non-linear relationship between BMI and impact of HS. As patients go from a low BMI patient to a high BMI patient (or from high to low), eruption patterns and risk factors may change. © 2017 European Academy of Dermatology and Venereology (EN)
English
Ερευνητικό υλικό ΕΚΠΑ
https://creativecommons.org/licenses/by-nc/4.0/
University of Athens
Pergamos Digital Library
Journal Article



*Institutions are responsible for keeping their URLs functional (digital file, item page in repository site)