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Childhood- and later-onset vitiligo have diverse epidemiologic and clinical characteristics

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Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών   

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Πέργαμος   

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Childhood- and later-onset vitiligo have diverse epidemiologic and clinical characteristics
Nicolaidou, E. Antoniou, C. Miniati, A. Lagogianni, E. Matekovits, A. Stratigos, A. Katsambas, A.
scientific_publication_article
Επιστημονική δημοσίευση - Άρθρο Περιοδικού (EL)
Scientific publication - Journal Article (EN)
2012
Background: Vitiligo onset during childhood is common. There are limited data regarding childhood-onset vitiligo. Objective: We sought to provide an epidemiologic and clinical comparison between childhood- and later-onset vitiligo. Methods: Two groups of patients were included in this cross-sectional study. Consecutive patients examined at the Vitiligo Clinic of Andreas Sygros Hospital for Skin and Venereal Diseases, Athens, Greece, from January 2005 to December 2009 with a disease onset before the age of 12 years were included in the childhood-onset group. The later-onset group included randomly selected patients who were examined at the same period and had a disease onset after the age of 12 years. After clinical examination, a standardized questionnaire was completed for each patient. Results: In all, 126 patients were included in the childhood-onset and 107 patients in the later-onset group. Childhood-onset vitiligo: (1) involved different sites at initial presentation, (2) included more cases of segmental type, and (3) was characterized by a higher prevalence of allergic diseases and a lower prevalence of thyroid diseases. Longer duration of disease and a positive family history of thyroid disease were associated with the presence of thyroid disease only in the childhood-onset group. In the later-onset group, only female sex was associated with the presence of thyroid disease. Limitations: The study was conducted in a hospital specializing in skin diseases and a selection bias toward more severe vitiligo cases is possible. Conclusions: Childhood-onset vitiligo had distinct epidemiologic and clinical characteristics, compared with later-onset disease. © 2011 by the American Academy of Dermatology, Inc. (EN)
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https://creativecommons.org/licenses/by-nc/4.0/
Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών
Πέργαμος
Άρθρο Περιοδικού (Journal Article)



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