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Determinants of exercise-induced ST segment depression in patients with coronary artery disease: A multivariate approach

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Determinants of exercise-induced ST segment depression in patients with coronary artery disease: A multivariate approach
Papazoglou, N. Kalpoyiannakis, I. Papazoglou, S.
scientific_publication_article
Επιστημονική δημοσίευση - Άρθρο Περιοδικού (EL)
Scientific publication - Journal Article (EN)
1997
The purpose of this study was to delineate among the usually gathered parameters in an electrocardiographic exercise test the determinants of its positive outcome (ΔST ↓ ≤ 1 mm measured at 80 msec from the J point). The authors studied 832 patients investigated with Bruce's exercise testing and with diagnostic coronary arteriography, all of whom were shown to have significant coronary artery disease (diameter stenosis ≤ 50%). Twenty-five demographic, clinical, electrocardiographic, exercise, and anatomic/hemodynamic parameters were analyzed. The stepwise forward logistic regression analysis retained seven among them as significant independent predictors: four as positive contributors: (1) three-vessel and/or left main disease (P=0.0000), (2) Gensini's angiographic score for disease extent (P=0.0025), (3) anginal pain during the test (P=0.0000), and (4) age (P=0.0031) and three as negative contributors: (1) resting heart rate (P=0.0004), (2) history of old myocardial infarction (P=0.0019), and (3) pathological Q waves at the resting ECG (P=0.0018). These findings establish standards that permit the prediction of the positive electrocardiographic exercise outcome in patients with significant coronary disease. (EN)
English
Ερευνητικό υλικό ΕΚΠΑ
https://creativecommons.org/licenses/by-nc/4.0/
University of Athens
Pergamos Digital Library
Journal Article



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